For many it is easier to tolerate and doesn't effect hearing loss. Cisplatin is still considered the gold standard - I honestly don't know why except it has been around for a long while and it's efficacy has been proven. Carboplatin was developed as a less toxic alternative.

That's a very good question Lois, since the article states that Cisplatin is more effective for head & neck cancers (but also has more toxic side effects). So once again we are back to the risk vs. benefit dilemma.

This article is probably already on the site but here is a link anyway: http://annonc.oxfordjournals.org/cgi/content/abstract/9/1/13