UPDATE for those in my shoes who come across this in the future. This particular chemo cocktail hasn't been that bad for me. It takes about a week to start to feel myself again. And day 3 after infusion is pretty miserable, but I get 2 weeks of feeling pretty normal and leading an active life for a 45 year old before having to go through it again. With my anti-nausea pills figured out it's not that bad.