thanks...I did discuss this with my dr already. Grapefruit Seed Extract (GSE) doesn't seem to illicit the same increase in absorption in the intestines that grapfruit itself does...though admittedly clinical testing is pretty limited. What testing has been done has shown zero toxicity and no interactions....

I guess I should add that I do have a degree in microbiology and fairly extensive medical background that includes 8 years in the US Navy as a Hospital Corpsman and Marine Field Medic, and the legal work I do involves extensive work with biotech and medical device companies. My girlfriend is also a microbiologist who works in virology developing vaccines. We both have studied oncology prior to this experience, and between us we certainly have kept the Dr's on their toes....one of them even asked me if I was an MD after I asked him some questions regarding the mechanisms of action for my chemo agents...he laughed when I said, "no I'm a lawyer..."

thanks all...
dw