Assistant Admin Patient Advocate (1000+ posts) Joined: Oct 2012 Posts: 1,275 Likes: 8 | Christine and PaulB have given you a lot of good information, the only thing I can add is make sure you find out what phase (1, 2, 3 or 4) the trial suggested to you is. You would like to find out if it is a double-blind trial. My husband was in two clinical trials. The first was for PDL 1, back in 2014. It was then a phase 1 trial. There were about thirty patients on that trial, and they had different cancers. According to our MO, who is in charge of drug development at the hospital, some patients showed tumor reduction, but it did not help my husband. Clinical trials are considered "palliative" in nature.
The second trial was a phase 2 trial for Selinexor which had some harsh side effects for John and he was eventually demitted from the trial.
With every clinical trial, there are conditions laid out by the drug developer the patient has to meet. For example, for the PDL 1 trial, there was some concern because John had Sjogren's Syndrome which is an auto-immune condition. He also was required to have a lung biopsy which itself carrried some risk. It was the developer who decided on eligibility, not the hospital or the doctor. The process of determining eligibility took a few weeks and so there was hope but also fear of getting "no" for an answer.
The one good thing was John was very closely monitored for all that time he was on the trials. We got a lot more face time with the doctors than otherwise.
I wish you all the very best. Please do keep posting to let us know how you are doing.
Last edited by gmcraft; 03-14-2017 07:14 AM.
Gloria She stood in the storm, and when the wind did not blow her way, she adjusted her sails... Elizabeth Edwards
Wife to John,dx 10/2012, BOT, HPV+, T3N2MO, RAD 70 gy,Cisplatinx2 , PEG in Dec 6, 2012, dx dvt in both legs after second chemo session, Apr 03/13 NED, July 2013 met to lungs, Phase 1 immunotherapy trial Jan 18/14 to July/14. Taxol/carboplatin July/14. Esophagus re-opened Oct 14. PEG out April 8, 2015. Phase 2 trial of Selinexor April to July 2015. At peace Jan 15, 2016. |