AK123, I'm sorry that you and Brandon are going through this again. It is extremely hard to be making these decisions. My husband was in a phase 1 immunotherapy trial last year. At the time, it was monotherapy, meaning he was given only the trial drug. We were told by our MO that she had patients on the drug who did show tumour reduction. So, it is a possibility that you might want to consider.

Gloria
She stood in the storm, and when the wind did not blow her way, she adjusted her sails... Elizabeth Edwards

Wife to John,dx 10/2012, BOT, HPV+, T3N2MO, RAD 70 gy,Cisplatinx2 , PEG in Dec 6, 2012, dx dvt in both legs after second chemo session, Apr 03/13 NED, July 2013 met to lungs, Phase 1 immunotherapy trial Jan 18/14 to July/14. Taxol/carboplatin July/14. Esophagus re-opened Oct 14. PEG out April 8, 2015. Phase 2 trial of Selinexor April to July 2015. At peace Jan 15, 2016.