 Patient Advocate (1000+ posts)
Joined: Jan 2013 Posts: 1,293 Likes: 1 | Thanks Paul for the links.
The first sort of echos the obvious in that weekly dosage is better tolerated than the larger 3 cycle. What was interesting was the 100 mg/m dosing was not tolerated by any of the patients, all failing to make the 3rd dose. They must have feeling poorly and got only 200 cum dosage.
The 80mg/m x 3 group got 240 but had to suffer the side effects of larger dosing. They must have felt pretty bad too.
The weekly dose of 40 mg/m x 6/6 actually delivered the same or more cumm dosing and better tolerated.
In my case, the MO observed my tolerance to TPF series and was very confident with a smile that the weekly carbo would be a breeze. In fact, I felt no chemo side effects so at least in my case I can vote for the obvious conclusion. :-)
Don Male, 57 - Great health except C Dec '12 DX: BOT SCC T2N2bMx, Stage 4a, HPV+, multiple nodes 1 tooth out Jan '13 2nd tooth out Tumor Board -induction TPF (3 cycles), seq CRT 4-6/2013 CRT 70gr 2x35, weekly carbo150 ended 5/29,6/4 All the details, join at http://beatdown.cognacom.com | 
