I' m still not completely comfortable about using the cisplatin again but hopefully a lesser dose administered over more time will be ok. I guess I will find out after the next one. 3 weeks done today. It has been really difficult to eat or drink this week. I found out I have thrush and am taking Diflucan. I hope this helps. My RO discourages having the PEG, But there is no way I can get enough nourishment the way it is now. I have unknown primary and they are radiating pretty much the whole area. I don't know if this makes it harder for me than most. Oh, back to the chemo, I've done some research and there are a few drugs, allopurinol and ebselen that have been tested in rats that reduce ototoxicity and nephrotoxicity from cisplatin. They are antioxidants, so they may interfere with the chemo.I guess I'm just reaching hear.Does anyone know anything about this?

Age 54 at DX 06/20/13 Left Neck Mass 07/11/13 DX SCC OC T0N2bM0 Stg IVa p16 neg. 08/09/13 Tonsilectomy and Adnoidectomy, Panendoscopy. Unknown Primary. Begin RAD 09/30/13 Cisplatin 10/01&22/13 PICC 10/21/13. PEG 10/25/13 to 1/24/14. Erbitux x 3. End 35 RAD 11/22/13 Clear PET 02/25/14