Thanks all for your comments. He has had pain issues for a while & every single med they try for that has made him sicker - that has been part of the problem and has resulted in the 3 hospital stays. The doctors in ER last time (after 9 hours of trying to stop nausea and pain sort of threw up their hands and said there is nothing else we can do for you) and discharged him. Until that LOW moment, I had had nothing but good experiences with them (including our previous 2 visits). Even the nurses were overheard saying they "avoided" his room because it is so heartbreaking and they can do nothing. I get what you are saying David but if I had been thru what he has with every single severe side effect, I would have put MYSELF out of misery so I hesitate to push more than I have- and I have pushed. He is so weak & skeletal from it all (though he eats faithfully thru the peg) that I just think his mind and body have gone the distance they can go. Sounds whimpy but......he was so weak and, as always, constantly vomiting ....the last ambulance pick up didn't even try to put in an IV. Still he did it all faithfully and on command until that last TX31.....something snapped.