There are clinical trials with HPV reduction in treatment, maybe with a Erbitux, but outside clinical trials it's not recommended, but Erbitux is used for first line treatment in HNC, and Cisplatin is the gold standard. There is still much unknown about HPV oropharyngeal cancer, and appears there may be three different sub types, one which is more high risk. Also, for some reason, HPV failure rates are being seen after 5 years, in distant areas not normally associated with HNC metastases. while non HPV, levels off after 2 years. I had Erbitux for metastic cancer, with taxotere, last November with the same side effects. Sounds like Erbitux was used as induction/neoadjunt treatment, but usually chemo or a tagged therapy is also used as a radio sensitizer during radiation.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs