This has been discussed in length, if you go to search, even before my time here, escpeiaaly by Charm, who recenty paseed. I made a link in one of my posts, probably last December, from MSKCC, number two CCC, sometimes number one, written to the editors of Journal of Clinical Oncology, regarding Erbitux, also known as Cetuximad. They do not recommend using it for definitive treatment in chemoradiation for locally advanced head and neck cancer outside clinical trials, due to disappointing findings. Also, they did not recommend using it with Cisplatin. There is a phase III trial going on that will show the efficacy of Cisplatin vs Erbitux, which is due to be completed in 2015. I see your signature has 3 chemo treatments, which sounds like the 3 big bag Cisplatin. Erbitux is usually given weekly, the first a loading dose, along with a Benadryl infusion, tylenol, and a lower dose, about half, the other weeks during your radiation treatment. Brian Hill made a post with Erbitux on a recent request from a member for treatment info with Orbitx or similar (sp). I will try to link the post when I get to my laptop. I had Ebitux last Oct/Nov, with Taxotere, but my treatments was for metastic recurrences, my 5th, and was not chemo naive, meaning I may have built a resistance to some chemo, have kidney disease now, so my choices are more limited.

http://jco.ascopubs.org/content/early/2012/11/30/JCO.2012.46.9049

Brian Hill's response with Erbitux is about 6 posts down, on Ina's post, Orbitux.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs