Cally, I'm glad your brother's treatment is doing good cancer wise. Even though he is relying on the peg, he should still try swallowing something, water, and exercise the mouth, tongue, jaw, and see a speech and swallow therapist, and a nutritionist to ensure adequate nutrion, and hydrarion, Some exercise are listed on the blog by Charm, I made several links to iswallow, showing, explaining at least 15 exercises, after medical clearance. As far as the mood, you say this is out out character. Cancer has an emotional impact on everyone from fear, treatment, pain, physical appearance change, being dependant in others, depression, loss of work, income, and suggest counseling, and some may need meds to help cope. Pain medications can also change ones behavior, as well as decadron, a corticosteroid, used with some types ov chemo, can make one more aggressive, even any chemical imbalances in the body. Maybe a support group meeting for H&N cancer, which many states here, a little walking fresh air dies wonders for the mind.
Another factor is being in constant fight mode to fight cancer, even insurance, and proper medical care, it sometimes gets mixed up where to end it, and often taken out of the ring, and on other people. Mostly I was quiet as a mouse, but could change to raging bull, If someone got in my way, made any slight towards me or was irritating.
I guess it takes a village to treat cancer, and it's difficult to do it alone.