Ativan is not powerful enough to quell the nausea from Cisplatin. They have SSRI type anti-nausea drugs (such as Zofran or Emend) that switch off the nausea center in the brain (well, most of the time anyway). Cisplatin also does a number on the GI tract, in general, so industrial strength antacids will be required as well, Famatodine (Pepcid AC), etc.

When I was getting Cisplatin I was nauseated most of the time until just before the next infusion and then it was exponentially worse. We all respond differently, however, so your experience might not be as bad.

You MUST drink lots of water daily during chemotherapy to protect your kidneys from damage, 2 liters/day I believe. Stay hydrated - it will also help mitigate the constipation issues.

As you are finding out this is no walk in the park but you can get through this - take it one day at a time.

Jim - TOO much information ;-)