My friend took emend and says it was a godsend. I have not been taking it as my MO says it's really expensive. She normally prescribes emend if the insurance will cover it. For now, though, she's giving me the plan B cocktail that doesn't cost as much to fill.
That being said, with my dosing regimen, I cannot stand Ethyol shots for the 2-3 days post chemo. Even if I don't feel nauseated, I refuse the shots for 2-3 days after chemo infusions. That seems to help quite a bit. I usually would have chemo on a Monday and start the Ethyol shots on Thursday or Friday, depending upon how I'm feeling.
Hopefully that helps.