#83378 11-02-2008 08:00 AM | Joined: Nov 2008 Posts: 1 Member | OP  Member
Joined: Nov 2008 Posts: 1 | I have been suffering from hyperkeratosed tissue on the anterior aspect of my upper palate for three years. I have been to a periondontist, as well as an oral surgeon, and was biopsied twice. The pathology reports were negative for malignancy, but indicated acanthosis and hyperkeratosis. Since there was no malignancy, the doctors became uninterested, and offered no treatment. From my reading, this sounds like symptoms of HPV in some cases. Are there any professionals who have experience with this? | | | | | Joined: Nov 2005 Posts: 1,128 Patient Advocate (1000+ posts) | | Patient Advocate (1000+ posts)
Joined: Nov 2005 Posts: 1,128 | Not a professional, but I had biopsies of mild dysplasia and hyperkeratosis from one spot on my tongue for 15 years before I finally grew a tumor (SCC) at that spot -- BTW, I had used tobacco and alcohol, but had quit tobacco 35 years and alcohol 11 years before the tumor -- Watchful Waiting is the key here, you become the expert on your mouth and get a biopsy when anything changes.
Age 67 1/2
Ventral Tongue SCC T2N0M0G1 10/05
Anterior Tongue SCC T2N0M0G2 6/08
Base of Tongue SCC T2N0M0G2 12/08
Three partial glossectomy (10/05,11/05,6/08), PEG, 37 XRT 66.6 Gy 1/06
Neck dissection, trach, PEG & forearm free flap (6/08)
Total glossectomy, trach, PEG & thigh free flap (12/08)
On August 21, 2010 at 9:20 am, Pete went off to play with the ratties in the sky.
| | | | | Joined: Sep 2006 Posts: 8,311 Senior Patient Advocate Patient Advocate (old timer, 2000 posts) | | Senior Patient Advocate Patient Advocate (old timer, 2000 posts)
Joined: Sep 2006 Posts: 8,311 | HPV is a virus with well over a 100 different strains and at least 4 of those have been associated with cancers including Oral Cancer. HPV+ oral cancers are most often associated with the Base of Tongue and Tonsils and most have spread to the lymph nodes on one or both sides of the neck before the cancer is discovered. While I'm certainly not an expert, I would assume that the cellular changes taking a normal cell to a cancerous one is similar when the HPV virus is the cause. Stay diligent but remember it's not cancer until it's been confirmed by a biopsy.
David
Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
| | | | | Joined: Mar 2002 Posts: 4,918 Likes: 67 OCF Founder Patient Advocate (old timer, 2000 posts) | | OCF Founder Patient Advocate (old timer, 2000 posts)
Joined: Mar 2002 Posts: 4,918 Likes: 67 | hyperkeratosis is not a mandatory precursor to malignancy. It happens for all kinds of reasons that are benign, irritation of a rough filling against the adjacent soft tissue with cause hyperkeratosis, or a toughening of the tissue to protect itself. This isn't something that is a known indicator of an oncoming negative event. it just is what it is. This doesn't mean you shouldn't watch the area for other developments, but by itself I wouldn't concern myself too much with this.
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
| | | | | Joined: Aug 2007 Posts: 580 "Above & Beyond" Member (500+ posts) | | "Above & Beyond" Member (500+ posts)
Joined: Aug 2007 Posts: 580 | Bill,
You say you have been "suffering" from hyperkeratosis of the anterior palate. Would you be so kind to let me know what symptoms your are experiencing? I would also like to know if you use tobacco and/or alcohol on a regular basis. How long ago did you first experience problems?
I'd like to try and help you if I can I just need a little more information in order to give you proper advice.
Contact me by PM or e-mail if you wish.
Cheers,
Mike
Dentist since 1995, 12 year Cancer Survivor, Father, Husband, Thankful to so many who supported me on my journey so far, and more than happy to comfort a friend.
Live, Laugh, Love & Learn.
| | |
| Forums23 Topics18,252 Posts197,147 Members13,332 | | Most Online1,788
Jan 23rd, 2025 | | |
|
