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#77608 07-27-2008 11:41 PM
Joined: Jan 2008
Posts: 179
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Senior Member (100+ posts)

Joined: Jan 2008
Posts: 179
Is anyone familiar with this type of chemo?


Dad: Age 65 Heavy smoker/drinker. Biopsy-No surgery. Cancer base of tongue/throat. "Invasive Squamous Carcinoma RRT" --Beginning 1/9/08: IMRT treatments (5X/wk),chemo pills (4/day) and Chemo IV (once/wk) PEG tube inserted 1/25/08. Treatments ended 2/26/08

JUNE 30, 2008 Officially CANCER FREE!!!
LarrysDaughter #77609 07-28-2008 02:03 AM
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its one of the many used in combination therapy.


Liz in the UK

Husband Robin aged 44 years Dx 8th Dec 2006 poorly differentiated SCC tongue with met to neck T1N2cM0 Surgery and Radiation.Finished TX April 2007
Recurrence June/07 died July 29th/07.

Never take your eye off the ball, it may just smack you in the mouth.
Cookey #77633 07-28-2008 03:10 PM
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Commonly given in a combination called ICE Ifosfamide, Carboplatin, and Etopicide also known as (VP-16). It is commonly given to people as an adjunct drug in lung cancers or mets to lungs. It screws with blood counts (like most chemo) and these require strict monitoring. Particularly low platelets, low white counts and the development of anemia. Also known as Vepesid.

There is a second generation version of this in clinical trials http://www.clinicaltrials.gov/ct/show/NCT00282022?order=2

I think if you look at this it will be interesting for anyone considering clinical trials (not the use of this drug as a combination therapy) because you can see how clinical trials are structured and how they target the population of people that are allowed in a trial in this example. This gives you some idea how difficult it can be to qualify for a clinical trial drug. Again not the specific drug you are asking about in this trial so pay no attention to the info in that link. This is an offspring of that drug.


Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.

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