#71272 03-10-2008 08:39 AM | Joined: Sep 2007 Posts: 79 Senior Member (75+ posts) | OP Senior Member (75+ posts) Joined: Sep 2007 Posts: 79 | Hello all, I was paging through my alumni magazine and a brief article about mucositis caught my eye. It seems that Dr. Cohen at the University of Chicago (my brother's oncologist) is working with scientists at the Argonne National Lab to try to predict which patients might have mucositis. They are in the midst of a two-year trial. The full article can be accessed here: http://magazine.uchicago.edu/0834/investigations/next_generation.shtml
Last edited by Brian Hill; 03-11-2008 03:47 PM.
* Root for Joe * Sister of Joe (43, non-smoker/chewer; occ. drinker). Mouth problem 3/07. Diag with Stage I 6/07. Diag with Stage IV 9/07. In EPOC at Univ of Chicago. Cisplatin/cetuximab 1/wk x 8. Then, IMRT 5x/wk x 7 and weekly chemo. Done 12/21/07. Looks good as of 4/08, 7/08, 8/08, 1/09.
| | | | Joined: Feb 2008 Posts: 341 Platinum Member (300+ posts) | Platinum Member (300+ posts) Joined: Feb 2008 Posts: 341 | Hi - it sounds like an interesting article, but I get the infamous "page not found error"... would you mind resending the link. THANKS!
Michelle, CG to husband (45), DX 2/08 Stage IVa Adenocarcinoma Salivary Gland (T2N2bMO) Parotidectomy & ND 2/08, Tumor margins not clear, 4 of 30 nodes positve for cancer, TX IMRT 39x, cisplatin 7x (completed 5/1/08), PEG (4/22 - 7/9), No port. Currently in remission!
| | | | Joined: Feb 2004 Posts: 598 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: Feb 2004 Posts: 598 | You just need to delete the period at the end of the link, which got caught in the copied URL. Jeff SCC Right BOT Dx 3/28/2007 T2N2a M0G1,Stage IVa Bilateral Neck Dissection 4/11/2007 39 x IMRT, 8 x Cisplatin Ended 7/11/07 Complete response to treatment so far!!
| | | | Joined: May 2006 Posts: 720 Likes: 1 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: May 2006 Posts: 720 Likes: 1 | Michelle -- The period at the end of the link should not be there. When you get the "page not found" message, just delete the period after shmtl in the address field, hit the Enter key and the article will appear.I see Jeff took care of that explanation. Alternatively, click here. -- Leslie
Last edited by Leslie B; 03-11-2008 12:28 PM.
Leslie
April 2006: Husband dx by dentist with leukoplakia on tongue. Oral surgeon's biopsy 4/28/06: Moderate dysplasia; pathology report warned of possible "skip effect." ENT's excisional biopsy (got it all) 5/31/06: SCC in situ/small bit superficially invasive. Early detection saves lives.
| | | | Joined: Mar 2002 Posts: 4,918 Likes: 67 OCF Founder Patient Advocate (old timer, 2000 posts) | OCF Founder Patient Advocate (old timer, 2000 posts) Joined: Mar 2002 Posts: 4,918 Likes: 67 | There are a variety of wound healing drugs and treatments in clinical trials. At the present time without them, this is interesting, but I don't see the application. A patient that is going to have severe mucocitis (I did, morphine level pain) isn't going to stop treatments that might save their lives in order to avoid mucocitis sores. They are going to tough it out, because the alternative is that the cancer will continue to gain ground if they do not. This is only relevant as a technology when there is something that is available that will counteract the development of mucocitis or reduce its impact. Knowing who is going to have the worst cases of it does not help right now.
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant. | | | | Joined: May 2007 Posts: 622 Likes: 1 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: May 2007 Posts: 622 Likes: 1 | [quote=Brian Hill] Knowing who is going to have the worst cases of it does not help right now. [/quote]
Other than being able to prepare the patient and/or the staff for it. It seemed to me that the doc and staff were in a mode of damage control with my mucoscitis sores instead of being proactive like they were on everything else.
Kevin 18 YEAR SURVIVOR SCC Tongue (T3N0M0) diag 06/2006. No evidence of disease 2010 Another PET 12-2014 pre-HBO, still N.E.D.
�Remember to look up at the stars and not down at your feet. It matters that you don't just give up.� Stephen Hawking | | | | Joined: Sep 2007 Posts: 79 Senior Member (75+ posts) | OP Senior Member (75+ posts) Joined: Sep 2007 Posts: 79 | Kevin, I agree with you. I am certainly not suggesting that someone not have treatment because of mucositis. I do think that knowing you might be more likely to have this effect would be helpful in terms of treatment path.
On a great side note - Joe had a check-up at U of C yesterday. They still can't do a biopsy because of all his tongue and mouth sores, but he is doing well and has started to regain some weight. More tests scheduled for April.
* Root for Joe * Sister of Joe (43, non-smoker/chewer; occ. drinker). Mouth problem 3/07. Diag with Stage I 6/07. Diag with Stage IV 9/07. In EPOC at Univ of Chicago. Cisplatin/cetuximab 1/wk x 8. Then, IMRT 5x/wk x 7 and weekly chemo. Done 12/21/07. Looks good as of 4/08, 7/08, 8/08, 1/09.
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