#66787 01-04-2008 03:47 AM | Joined: Sep 2006 Posts: 8,311 Senior Patient Advocate Patient Advocate (old timer, 2000 posts) | OP Senior Patient Advocate Patient Advocate (old timer, 2000 posts) Joined: Sep 2006 Posts: 8,311 | Here's a link to a new testing procedure from Johns Hopkins that I saw on the news last night. http://www.tampabays10.com/news/health/article.aspx?storyid=71071Lets hope they continue to find more and more early detection techniques and lets hope primary care physicians including dentists see if this can be implemented into their routine exams. I am e mailing all the doctors & my long term dentist that examined me before, during and since my Tx ended even though this test doesn't appear to benefit HPV+ patients. I suggest everyone here do the same to help spread this technique. Imagine how many doctors we can tell in one day!!
Last edited by davidcpa; 01-04-2008 03:57 AM.
David
Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
| | | | Joined: Jun 2007 Posts: 5,260 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Jun 2007 Posts: 5,260 | david,, thanks for posting this info. It sure would be nice to detect OC this way instead of all the hit and miss we have had to do. Good Job there old buddy.
Since posting this. UPMC, Pittsburgh, Oct 2011 until Jan. I averaged about 2 to 3 surgeries a week there. w Can't have jaw made as bone is deteroriating steaily that is left in jaw. Mersa is to blame. Feeding tube . Had trach for 4mos. Got it out April. --- Passed away 5/14/14, will be greatly missed by everyone here
| | | | Joined: Aug 2006 Posts: 199 Senior Member (100+ posts) | Senior Member (100+ posts) Joined: Aug 2006 Posts: 199 |
Ginny M. SCC of Left lateral tongue Dx 04/06,Surgery MDACC 05/11/06: Partial glossectomy with selective neck dissection. T1N0M0 - no radiation. Phase III clinical trial ("EPOC" trial)04/07 thru 04/08 because tests showed a 65% chance of recurrence. 10 Year Survivor!
| | | | Joined: Mar 2002 Posts: 4,918 Likes: 66 OCF Founder Patient Advocate (old timer, 2000 posts) | OCF Founder Patient Advocate (old timer, 2000 posts) Joined: Mar 2002 Posts: 4,918 Likes: 66 | This test is a very early result of Califano's team's work. It is a long way from being an FDA approved test, and the work has to be duplicated in other institutions. More important, a test that is less than 50% effective at finding disease isn't very good by comparisons to other tests we commonly think of. It is far more likely that the saliva diagnostic test which was developed by OCF board member Dr. David Wong at UCLA, will become commercialized sooner than this swish test (if this one ever is). It has been replicated at 4 institutions, and not only has been shown to find oral cancers (of any origin) but will also find things like diabetes, breast cancer, and possibly next, early Alzheimer's in people. It already has some giant pharma/diagnostics companies looking at it to take to market.
The UCLA team are mapping the RNA and associated proteins for other diseases even as we speak to add to the assay the test can do. The NIH is very hot on the technology, and has spent about 60 million dollars in research on it so far. The test out of JH has a huge down side, and that is that the cost of analyzing the saliva solution is VERY expensive, making it perhaps prohibitive as a commercial product. On the other hand the salivary diagnostic test at UCLA is analyzed by a simple preprogrammed computer chip, that looks for certain biomarker factors in the saliva and is very inexpensive to do, making it an ideal mass screening tool, that anyone, not even a doctor, can administer. OCF has been a financial research supporter to the Wong idea early in the process, and we have been posting in the news section about the developments of the work for almost 5 years. (Search the news section for articles that have the words Wong, or UCLA in them.)
The technology of the swish test is interesting, but does not use any really new technique. More than that, things like this are developed all the time - the proof is if a big company with the financial resources to do so, will become interested enough to spend the millions to bring it to market and commercialize the idea. JH's test will likely never get over that particular obstacle.
As a side note, if people would subscribe to the free RSS feed from OCF
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant. | | | | Joined: Feb 2005 Posts: 2,019 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Feb 2005 Posts: 2,019 | NPR's "Talk of the Nation-Science Friday" is having a segment on these tests today in just a couple of hours, in case anyone is interested in further details (or calling in with questions or comments)! http://www.sciencefriday.com/
SCC(T2N0M0) part.glossectomy & neck dissect 2/9/05 & 2/25/05.33 IMRT(66 Gy),2 Cisplatin ended 06/03/05.Stage I breast cancer treated 2/05-11/05.Surgery to remove esophageal stricture 07/06, still having dilatations to keep esophagus open.Dysphagia. "When you're going through hell, keep going"
| | | | Joined: Jul 2007 Posts: 939 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: Jul 2007 Posts: 939 | Can someone subscribe to the RSS Feeds and see if the link works??
I am getting an error message saying "IE cannot display..contains code errors."
Is it me or a bad link?? Tks, Deb
Deb..caregiver to husband, age 63 at diagnosis, former smoker who quit in 1997. DIAGNOSIS: 6/26/07 SCC right tonsil/BOT T4N0M0 TREATMENT START: 8/9/07 cisplatin/taxol X 7..IMRT twice daily X 31.5. TREATMENT END: 10/1/07 PEG OUT: 1/08 PORT OUT: 4/09 FOLLOWUP: Now only annual exams. ALL CLEAR!
Passed away 1/7/17 RIP Bill
| | | | Joined: May 2007 Posts: 666 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: May 2007 Posts: 666 | Deb it works for me: http://www.oralcancerfoundation.org/news/index.aspClick here to subscribe to our oral cancer in the news RSS feed ---> works I have not played with this perhaps you need to enable cookies? (I am using Safari (Mac, OSX) (Setup: Enable plug-ins, enable Java Script, Accept cookies=always) On the mac you can select the RSS stream also as a screen saver, very cool. M
Last edited by Markus; 01-04-2008 09:01 AM. Reason: stupid typo!
Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
| | | | Joined: Feb 2005 Posts: 2,019 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Feb 2005 Posts: 2,019 | Just wanted to say that you can now listen to the Science Friday" interview with the doc at Johns Hopkins by clicking on this link. http://www.sciencefriday.com/ He said he thought this test would be available at least for oral cancer patients, who are at higher risk for recurrence, within 5 years. I would gladly be in a clinical trial before then--even more so for the one that can detect breast cancer too! Is there a way to find out when and where those trials become available? Nelie
SCC(T2N0M0) part.glossectomy & neck dissect 2/9/05 & 2/25/05.33 IMRT(66 Gy),2 Cisplatin ended 06/03/05.Stage I breast cancer treated 2/05-11/05.Surgery to remove esophageal stricture 07/06, still having dilatations to keep esophagus open.Dysphagia. "When you're going through hell, keep going"
| | | | Joined: Sep 2006 Posts: 8,311 Senior Patient Advocate Patient Advocate (old timer, 2000 posts) | OP Senior Patient Advocate Patient Advocate (old timer, 2000 posts) Joined: Sep 2006 Posts: 8,311 | I also can not go to that link on the page. I get the Page cannot be dispalyed screen and the XML page cannot be displayed screen.
David
Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
| | | | Joined: Mar 2002 Posts: 4,918 Likes: 66 OCF Founder Patient Advocate (old timer, 2000 posts) | OCF Founder Patient Advocate (old timer, 2000 posts) Joined: Mar 2002 Posts: 4,918 Likes: 66 | URL works fine. feed://feeds.feedburner.com/oralcancernews
Once you open this page just drag it down to your browser header with your other favorites. When new news is added to it a number of new article will appear next to it.
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant. | | |
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