#66752 01-03-2008 09:35 AM | Joined: Sep 2006 Posts: 1,357 Likes: 5 "OCF Canuck" Patient Advocate (1000+ posts) | OP "OCF Canuck" Patient Advocate (1000+ posts) Joined: Sep 2006 Posts: 1,357 Likes: 5 | I get my first Cisplatin treatment on Tuesday - they are being given in conjunction with another 33 radiation treatements. I remember vividly the radiation - but what should I expect from Cisplatin? Any help would be appreciated.
Donna
Donna,69, SCC L Tongue T2N1MO Stg IV 4/04 w/partial gloss;32 radtx; T2N2M0 Stg IV; R tongue-2nd partial gloss w/graft 10/07; 30 radtx/2 cispl 2/08. 3rd Oral Cancer surgery 1/22 - Stage 1. 2022 surgery eliminated swallowing and bottom left jaw. Now a “Tubie for Life”.no food envy - Thank God! Surviving isn't easy!!!! .Proudly Canadian - YES, UNIVERSAL HEALTH CARE IS WONDERFUL! (Not perfect but definitely WONDERFUL)
| | | | Joined: Jun 2007 Posts: 718 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: Jun 2007 Posts: 718 | My husband had one treatment of Cisplatin. They had him take anti nausea medications before, during and after the treatment. And, they gave him extra hydration.
The unexpected thing for him is that one of the meds they gave him prior to the Cisplatin made him really, really sleepy. So, I was glad I was along to drive him home.
Also, I remember it was a long day and we brought along board games and cards. We managed to play until he fell asleep somewhere along the way.
Some people get a lot of nausea. He did not get any. In fact, he felt quite well that following week. I wish you well! Margaret ---------- C/G: Husband, 48 (at time of dx) Dx 5/18/07 SCC, BOT, lymph node involvement. T1N2BM0. (Stage 4a, G2/3) Tx 6/18 - 8/3/07, IMRT x 33 Cisplatin x3 (stopped after 1st dose due to hearing issues). Weekly Erbitux started 6/27/07 completed 8/6/07.
| | | | Joined: May 2007 Posts: 632 "Above & Beyond" Member (300+ posts) | "Above & Beyond" Member (300+ posts) Joined: May 2007 Posts: 632 | Good luck with the treatment Donna. I was told, with any chemo, water, water and more water! And to take anti-nausea meds BEFORE feeling sick, so as not to set up a vicious nausea/not eating circle. Brenda
Brenda in UK--Diagnosis 30/5/07--undifferentiated carcinoma in right jawbone and muscles. Stage 4 6/7/07--new diagnosis primary is in lung. Finished 4cycles of palliative carboplatin/gemcitabine therapy September 07 Now dying to live!
| | | | Joined: May 2007 Posts: 666 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: May 2007 Posts: 666 | The reactions to cisplatin can vary widely. It also GREATLY depends how much you are getting. Some people are scheduled for 3 tx 3 weeks apart while others get it weekly. If you are getting this weekly (and only a third of the dose) then the side effects are normally less. I had 2 cisplatin treatments. About 3 days after the first infusion I started to get the ringing. I informed my MO and he figured that this was just in my head (no kidding!!). Well it went mostly away by the time the second infusion was due. And then it got really annoying. We switched to carboplatin. Which they then they tell you is "just" as good as cisplatin but with fewer side effects...... If you can tolerate it stick with cisplatin there is more data for it. I never felt tired from the cisplatin, however consider they I had a lower dose because I got it weekly and it was at the beginning of the rad tx as well. I got all kinds of nausea pills which I did not end up using at all. For the cisplatin I only had trouble exactly two days before the next treatment and I took a pill the night before. Once we switched to carboplatin I did not even have to do that. Although I got both rad and cisplatin at the same time I would rate the chemo as "benign" compared to the rad tx later on. Best
Markus
Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
| | | | Joined: Jun 2007 Posts: 214 Gold Member (200+ posts) | Gold Member (200+ posts) Joined: Jun 2007 Posts: 214 | The only side effect I got from was from the anti-nausea meds themselves, not the cisplatin. The meds can cause extreme constipation in some people. Once we got a grip on that after the first treatment, I didn't have any problems.
Left tonsil SCC, HPV+. T2N0M0. Tonsillectomy 3-07, bilateral radiation, cisplatin 3x, Tx completed 6-06. Clear PET 4-01-2008. Thyroidectomy 5-9-08, resulting in permanent surgically-induced hypoparathyroidism and adrenal problems. Bummer. | | | | Joined: Sep 2006 Posts: 8,311 Senior Patient Advocate Patient Advocate (old timer, 2000 posts) | Senior Patient Advocate Patient Advocate (old timer, 2000 posts) Joined: Sep 2006 Posts: 8,311 | Donna,
I had 3 Cis' 3 weeks apart. The first was before my first Rad Tx and the last was before my last Rad Tx. All were given before I went to the rad room so those were 3 very long days.
I was given a very strong anti nausea med that cost me $100 a pill. I had to take one before each Tx and then 1 a day for the next 2 days. I was told not to let my wife come in contact with any of my body fluids including sweat during the 3 days after each Tx.
I really had no reaction to the first bag but the 2nd bag right before my 16th rad tx hit me pretty hard re nausea. I had a hard time with nausea from that point on so it could have just been me.
I also experienced ringing in my ears but I didn't recognize it at the time. I mean it's not like RINGING in your ears but once you finally recognize it you can see why it's described as "ringing". I didn't recognize the ringing as ringing until after my 3rd Tx and that's when my MO reminded me that he had told me the ringing is actually damage being done to your ears. He said some experience it and some don't. He told me that if I had told him sooner he would have switched me to Carbo P because as he put it, it's just as effective as Cis but without the hearing loss potential. I asked him then why in the world didn't he use Carbo from the getgo and he said that there was more published results on Cis. Oh well, I did end up with some permanent high frequency hearing loss but like many other side effects we have to put up with this cancer Tx, it's not that bad. I would still have preferred not to have the HF loss so if I were you I would ask about Carbo.
David
Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
| | | | Joined: Nov 2002 Posts: 3,552 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Nov 2002 Posts: 3,552 | Check out the FAQ section I moved a topic about Cisplatin from the archives
Gary Allsebrook *********************************** Dx 11/22/02, SCC, 6 x 3 cm Polypoid tumor, rt tonsil, Stage III/IVA, T3N0M0 G1/2 Tx 1/28/03 - 3/19/03, Cisplatin ct x2, IMRT, bilateral, with boost, x35(69.96Gy) ________________________________________________________ "You are a mist that appears for a little while and then vanishes" (James 4:14 NIV)
| | | | Joined: Jun 2007 Posts: 221 Gold Member (200+ posts) | Gold Member (200+ posts) Joined: Jun 2007 Posts: 221 | Gary,
Excellent thread! Thanks!
Joy
CG to Father, 75 yo with SCC of the mouth; upper maxillectomy and neck diss. performed on 5/23/07. Father also suffered heart attack during surgery and now has CHF. RT complete on 8/28/07. Cancer back 11/27/07. RT and Chemo to start on 12/17. Cancer back 6/17/08. Finally at rest 08/08/08.
| | | | Joined: Aug 2006 Posts: 294 Gold Member (200+ posts) | Gold Member (200+ posts) Joined: Aug 2006 Posts: 294 | I immediately experienced ear ringing which I still have today a year and a half later. I was warned to watch for the ringing at the time and I told of it accordingly. I was taken off Cisplatin at that time and also put on Carboplatin.
Bill D.
Dx 4/27/06, SCC, BOT, Stage III/IV, Tx 5/25/06 through 7/12/06 - 33 IMRT and 4 chemo, radical right side neck dissection 9/20/06.
| | | | Joined: Sep 2006 Posts: 1,357 Likes: 5 "OCF Canuck" Patient Advocate (1000+ posts) | OP "OCF Canuck" Patient Advocate (1000+ posts) Joined: Sep 2006 Posts: 1,357 Likes: 5 | Thank you all! I now feel much more prepared and aware of what to watch for. I now feel much less apprehensive about the treatment. You guys are invaluable!
Donna
Donna,69, SCC L Tongue T2N1MO Stg IV 4/04 w/partial gloss;32 radtx; T2N2M0 Stg IV; R tongue-2nd partial gloss w/graft 10/07; 30 radtx/2 cispl 2/08. 3rd Oral Cancer surgery 1/22 - Stage 1. 2022 surgery eliminated swallowing and bottom left jaw. Now a “Tubie for Life”.no food envy - Thank God! Surviving isn't easy!!!! .Proudly Canadian - YES, UNIVERSAL HEALTH CARE IS WONDERFUL! (Not perfect but definitely WONDERFUL)
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