#55215     07-25-2004 02:36 AM      |       Joined:  Apr 2004  Posts: 156    Gold Member (100+ posts)   |      OP      Gold Member (100+ posts)    Joined:  Apr 2004  Posts: 156  |    In a prior post I noticed a lot of complaints regarding Salagen and sweating.  I ran a search on Evoxac and didn't really see any comments on it.  Has any tried it, found it useful, had side effects, etc.?
  For those unaware, apparently these two drugs aid in the dry mouth area.  
  Thanks, Sabrina      |      |       |                      
#55216     07-25-2004 05:04 AM      |       Joined:  May 2003  Posts: 41    Contributing Member (25+ posts)   |           Contributing Member (25+ posts)    Joined:  May 2003  Posts: 41  |    Hi Sabrina, I was on a clinical trial for 1 year with Evoxac, it didn't help me. I didn't notice any saliva increase (I have almost none) while on the medicine, and no change after I stopped taking it. I had no side effects that I noticed. One of the listed side effects is reduced night vision. I have heard of good results with Evoxac, but that may be with folks who have more salivary function. O-O        
Head and neck SCC TXN2bM0 stage IV Finished treatment 6/02
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#55217     07-25-2004 08:13 AM      |       Joined:  Dec 2003  Posts: 2,606 Likes: 2    Patient Advocate (old timer, 2000 posts)   |           Patient Advocate (old timer, 2000 posts)    Joined:  Dec 2003  Posts: 2,606 Likes: 2  |    Sabrina,
  I spent several months on Salagen and Evoxac.  I haven't taken either for about two months and I didn't really notice much difference with either drug in regards to less dry mouth.  I had about the same experience sweating with both and sweated more when the temperature was cooler for some odd reason.
  Ed        
SCC Stage IV, BOT, T2N2bM0 Cisplatin/5FU x 3, 40 days  radiation Diagnosis 07/21/03 tx completed 10/08/03 Post Radiation Lower Motor Neuron Syndrome 3/08.  Cervical Spinal Stenosis  01/11 Cervical Myelitis 09/12 Thoracic Paraplegia 10/12 Dysautonomia 11/12 Hospice care 09/12-01/13. COPD 01/14 Intermittent CHF 6/15 Feeding tube NPO 03/16 VFI 12/2016 ORN 12/2017 Cardiac Event 06/2018 Bilateral VFI 01/2021 Thoracotomy Bilobectomy  01/2022 Bilateral VFI 05/2022 Total Laryngectomy 01/2023
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#55218     07-25-2004 10:16 AM      |       Joined:  Apr 2004  Posts: 837    "Above & Beyond" Member (300+ posts)   |           "Above & Beyond" Member (300+ posts)    Joined:  Apr 2004  Posts: 837  |    Sabrina,
  I've been using Salagen for over 13 years (5mg 3 times a day), and I definitely notice a reduction in saliva if I miss a dose.  In my case, the sweating from Salagen seems to be minimal if I take the pills most of the way through mealtime.  (Now if I could only kill off the hot flashes -- that's a whole nother sweating story!)
  Cathy        
Tongue SCC (T2M0N0), poorly differentiated, diagnosed 3/89, partial glossectomy and neck dissection 4/89, radiation from early June to late August 1989
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