#41779 09-06-2007 05:35 AM | Joined: Sep 2007 Posts: 4 Member | OP Member Joined: Sep 2007 Posts: 4 | I have not started treatment yet but I have one group of physicians recommending adjunctive chemo treatment and another group that has has indicated that chemo might not be indicated in my case, I'm confused...Please help | | |
#41780 09-06-2007 07:31 AM | Joined: Feb 2007 Posts: 1,940 "OCF across the pond" Patient Advocate (1000+ posts) | "OCF across the pond" Patient Advocate (1000+ posts) Joined: Feb 2007 Posts: 1,940 | Without knowing your diagnosis or staging ect michael it will be difficult for people to advise or comment.Could you put a bit more flesh on the bones?
Liz in the UK
Husband Robin aged 44 years Dx 8th Dec 2006 poorly differentiated SCC tongue with met to neck T1N2cM0 Surgery and Radiation.Finished TX April 2007 Recurrence June/07 died July 29th/07.
Never take your eye off the ball, it may just smack you in the mouth.
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#41781 09-06-2007 04:03 PM | Joined: Nov 2002 Posts: 3,552 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Nov 2002 Posts: 3,552 | Adjunctive chemo can add an as much as 13% improved outcome by enhancing the radiation. It is toxic however and SOME experience various side effects from it from temporary to permanent. These effects can be managed by your team.
I personally have had more problems with side effects from the radiation than the chemo. Nothing that slows me down or stops me from enjoying life.
Typically adjunctive chemo is indicated mainly for stage 2 or higher, stage 2 being on the fence. Stage 3 or higher I wouldn't even consider not having it.
Gary Allsebrook *********************************** Dx 11/22/02, SCC, 6 x 3 cm Polypoid tumor, rt tonsil, Stage III/IVA, T3N0M0 G1/2 Tx 1/28/03 - 3/19/03, Cisplatin ct x2, IMRT, bilateral, with boost, x35(69.96Gy) ________________________________________________________ "You are a mist that appears for a little while and then vanishes" (James 4:14 NIV)
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#41782 09-06-2007 04:31 PM | Joined: Mar 2002 Posts: 4,918 Likes: 65 OCF Founder Patient Advocate (old timer, 2000 posts) | OCF Founder Patient Advocate (old timer, 2000 posts) Joined: Mar 2002 Posts: 4,918 Likes: 65 | Gary has this right in my book. The long term quality of life issues come from the grays of radiation, not the chemo. I'm a "hit it with the biggest hammer possible from the get go" kind of guy. You don't want to think about recurences down the road, and getting it all, including micro mets now, is a good path. Will it be more taxing on you personally for awhile? Yes, but that will pass.
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant. | | |
#41783 09-06-2007 04:40 PM | Joined: Aug 2007 Posts: 580 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: Aug 2007 Posts: 580 | Agressive diagnosis and agressive treatment in my books equals better chance of recovery and a better outlook for the future.
Mike
Dentist since 1995, 12 year Cancer Survivor, Father, Husband, Thankful to so many who supported me on my journey so far, and more than happy to comfort a friend. Live, Laugh, Love & Learn.
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#41784 09-06-2007 07:10 PM | Joined: Feb 2007 Posts: 1,940 "OCF across the pond" Patient Advocate (1000+ posts) | "OCF across the pond" Patient Advocate (1000+ posts) Joined: Feb 2007 Posts: 1,940 | I wish Robins surgeons had felt that way.Their confidence in just surgery and radiation was obviously misplaced and cost him a chance at survival.When he was diagnosed and staged he was expected to make a full and complete recovery ,but this disease is no respector of statistics or even expectations. Hit it hard with everything you have and give youself the very best shot at beating it.
liz
Liz in the UK
Husband Robin aged 44 years Dx 8th Dec 2006 poorly differentiated SCC tongue with met to neck T1N2cM0 Surgery and Radiation.Finished TX April 2007 Recurrence June/07 died July 29th/07.
Never take your eye off the ball, it may just smack you in the mouth.
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#41785 09-07-2007 09:31 AM | Joined: May 2007 Posts: 666 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: May 2007 Posts: 666 | I also had adjunctive chemo, initially cisplating and then carboplatin. Used this way the chemo is a radiosensitizer as Gary already said.
I had this weekly (a total of 7 times) and at least in my case the effects of the chemo were not an issue, although I did end up with a low white cell blood count (from carboplatin). .... For which they have another injection (neupogen not a big deal).
Markus
Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
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#41786 09-12-2007 12:34 PM | Joined: Sep 2007 Posts: 4 Member | OP Member Joined: Sep 2007 Posts: 4 | Sorry for the slow reply, I've been away. I have a T1, N1 diagnosis. I have read some recent studies that indicate that ct may not have a necessarily positive potentiating effect on cases similar to mine. I have also read that HPV instigated tumors respond well to radiation treatment alone. | | |
#41787 09-29-2007 07:34 AM | Joined: Sep 2007 Posts: 6 Member | Member Joined: Sep 2007 Posts: 6 | Dear Michael, T1, N1 of what? I assume it must be tongue. The standard of care is RT after surgery. Cisplatin and Paclitaxel have been used as potentiating agents but the exact effect on improvement has not been quantified. I suggest RT definitely. Chemo would be weekly schedule and optional. ALL THE VERY BEST TO YOU CHIEF! Love, Dileep
Dileep :-) Ca Rt BM, T1 N0 M0, Surgery with palatal flap and STG 2nd Aug 2007.Here's to life. Dont let the pain get to you! Know that you are alive to experience it!!
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