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Joined: Jul 2006
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Joined: Jul 2006
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I'm curious to know if anyone knows about some type of throat lozenges that is supposed to be good for you while being treated with chemo/radiation, but its not sold in the USA......? I read about it from someone on this site but can't seem to find it.


squam cell carcin base of tongue 5 out of 33 lympth nodes effected & removed w/ neck surgery on 6/27/06
33 treatments of IMRT & 2 cycles of cisplatin
Joined: Jul 2005
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The lozenges (there is also a mouth rinse) are called Difflam and contain benzydamine HCl, which has been shown in a number of clinical trials to be best for reducing the severity and duration of radiation and chemo-induced mucositis, It is, however, not yet approved by FDA although it has been in over 37 countries according to our dental oncologst (who participated in a USA trials and said it does work) -- he is irritated at the delay in approval since it is a topical NSAID, is not ingested, and relieves a lot of suffering. Have to assume FDA has some concerns, maybe they are super-careful now about new NSAIDs.

However, that is beside the point. It is available by prescription as a mouth rinse in Canada (as Tantum) and in UK, Europe, Australia and a number of other countries over-the-counter as a mouth rinse called Difflam. The lozenges are not available in UK, as my husband found out when he visited home in May, but are available in Australia and NZ. An Aussie friend brought him some on a visit in December and Barry thought they really helped his throat heal.

Gail


CG to husband Barry, dx. 7/21/05, age 66, SCC rgt. tonsil, BOT, 2 nodes (stg. IV), HPV+, tonsillectomy, 7x carboplatin, 35x tomoTherapy IMRT w/ Ethyol @ Johns Hopkins, thru treatment 9/28/05, HPV vaccine trial 12/06-present. Looking good!
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