#39250 10-07-2005 11:01 AM | Joined: Jun 2005 Posts: 349 Likes: 2 Platinum Member (300+ posts) | OP  Platinum Member (300+ posts)
Joined: Jun 2005 Posts: 349 Likes: 2 | Here's a link to the actual study facts in case anyone is interested. http://www.medpagetoday.com/tbprint.cfm?tbid=1886
Michael | 53 | SCC | Right Tonsil | Dx'd: 06-10-05 | STAGE IV, T3N2bM0 | 3 Nodes R Side | MRND & Tonsillectomy 06/29/05 Dr Fee/Stanford | 8 wks Rad/Chemo startd August 15th @ MSKCC, NY | Tx Ended: 09-27-05 | Cancer free at 16+ Yrs | After-Effects of Tx: Thyroid function is 0, ok salivary function, tinnitus, some scars, neck/face asymmetry, gastric reflux. 2017 dysphagia, L Carotid stent / 2019, R Carotid occluded not eligible for stent.2022 dental issues, possible ORN, memory/recall challenges.
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#39251 10-07-2005 04:22 PM | Joined: Oct 2005 Posts: 14 Member | | Member
Joined: Oct 2005 Posts: 14 | Thanks Michael...
No mention of oral cancer at this point. But hopefully this is the beginning of something.
Tom
Stage 3, T3,N1,M0, Squamous Cell Carcinoma, Base of Tongue. Surgery, Radiation 6 weeks. Completed Treatment Sep 2005. Recurrence Jun 2006 - Chemo Gemcitabine/Paclitaxol Nov 2006
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#39252 10-08-2005 02:30 PM | Joined: Mar 2002 Posts: 4,918 Likes: 66 OCF Founder Patient Advocate (old timer, 2000 posts) | | OCF Founder Patient Advocate (old timer, 2000 posts)
Joined: Mar 2002 Posts: 4,918 Likes: 66 | Please everyone read the very first lead in to the study * Explain to patients that the vaccine is not yet available clinically but the results of this clinical trial are promising. * Note that the vaccine covers 70% of the strains of HPV that cause cancer and, therefore, will not prevent all cervical cancer. * This study was published as an abstract and presented orally at a conference. These data and conclusions should be considered to be preliminary as they have not yet been reviewed and published in a peer-reviewed publication. Also please note that this is not the TREATMENT vaccine that has been in the works for years and will be years yet to come.
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
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#39253 10-08-2005 02:47 PM | Joined: Feb 2005 Posts: 2,019 Patient Advocate (old timer, 2000 posts) | | Patient Advocate (old timer, 2000 posts)
Joined: Feb 2005 Posts: 2,019 | Actually, there was some news show covering this that I was watching yesterday (CNN? PBS? They all announced it in the last couple of days) where they did mention oral cancer at the end in terms of other cancers that may be related to HPV and which may eventually be partially preventable through a vaccine. Its big news in itself I gather partly because its the first example of what appears to be an effective vaccine for a viral cause of cancer.
SCC(T2N0M0) part.glossectomy & neck dissect 2/9/05 & 2/25/05.33 IMRT(66 Gy),2 Cisplatin ended 06/03/05.Stage I breast cancer treated 2/05-11/05.Surgery to remove esophageal stricture 07/06, still having dilatations to keep esophagus open.Dysphagia. "When you're going through hell, keep going"
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#39254 10-09-2005 07:22 AM | Joined: Jun 2005 Posts: 349 Likes: 2 Platinum Member (300+ posts) | | OP Platinum Member (300+ posts)
Joined: Jun 2005 Posts: 349 Likes: 2 | Brian, there IS a "treatment" vaccine in the works too?
At least there is still hope.
Did you read the latest Cox-2 study?
Iressa
Michael | 53 | SCC | Right Tonsil | Dx'd: 06-10-05 | STAGE IV, T3N2bM0 | 3 Nodes R Side | MRND & Tonsillectomy 06/29/05 Dr Fee/Stanford | 8 wks Rad/Chemo startd August 15th @ MSKCC, NY | Tx Ended: 09-27-05 | Cancer free at 16+ Yrs | After-Effects of Tx: Thyroid function is 0, ok salivary function, tinnitus, some scars, neck/face asymmetry, gastric reflux. 2017 dysphagia, L Carotid stent / 2019, R Carotid occluded not eligible for stent.2022 dental issues, possible ORN, memory/recall challenges.
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#39255 10-09-2005 11:56 AM | Joined: Mar 2002 Posts: 4,918 Likes: 66 OCF Founder Patient Advocate (old timer, 2000 posts) | | OCF Founder Patient Advocate (old timer, 2000 posts)
Joined: Mar 2002 Posts: 4,918 Likes: 66 | This is a PHASE ONE trial.... Please do not post things about early trials like this. Besides Shel is on top of this stuff in the news section. When they get to stage three, years from now, the conclusions will be bearing fruit or not. Stage one trials don't even have an idea of dosing levels, and there is more that is unknown from them. They are VERY PRELIMINARY. Over the next few years targeted therapies may be a reality for H&N patients, and Irressa which didn't do so well in other cancers, may find a niche. But I think that it is more important for you to be thinking about living your life right now, getting mentally back on your feet, ENJOYING survivorship, than thinking about a drug that might help a person in recurrence...which if you are LUCKY, will never be part of your personal vocabulary. COX 2 inhibitors have been explored for at least 10 years in this arena, and if you read some of my old treads on chemoprevention, I was even taking them since the data looked good. Of course that's before we realized that they had a link to causing heart issues. There are some herbal COX 2 inhibitors, and the best one seems to be one called Inflamed, but they are significantly weaker than the inhibitors that were used in the early COX 2 trials. I take this stuff for all my old injuries that are now painful. Don't get trapped in being a study wonk
Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
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#39256 11-01-2005 04:57 AM | Joined: Jun 2005 Posts: 349 Likes: 2 Platinum Member (300+ posts) | | OP Platinum Member (300+ posts)
Joined: Jun 2005 Posts: 349 Likes: 2 | Sorry to continue to be the dumb optimist, but I thought some might like to read the latest I found on HPV vaccines. It's VERY EARLY I realize, but for some it may prove to be helpful. http://www.medpagetoday.com/tbprint.cfm?tbid=2036 - Michael
Michael | 53 | SCC | Right Tonsil | Dx'd: 06-10-05 | STAGE IV, T3N2bM0 | 3 Nodes R Side | MRND & Tonsillectomy 06/29/05 Dr Fee/Stanford | 8 wks Rad/Chemo startd August 15th @ MSKCC, NY | Tx Ended: 09-27-05 | Cancer free at 16+ Yrs | After-Effects of Tx: Thyroid function is 0, ok salivary function, tinnitus, some scars, neck/face asymmetry, gastric reflux. 2017 dysphagia, L Carotid stent / 2019, R Carotid occluded not eligible for stent.2022 dental issues, possible ORN, memory/recall challenges.
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#39257 11-01-2005 01:00 PM | Joined: Jun 2005 Posts: 349 Likes: 2 Platinum Member (300+ posts) | | OP Platinum Member (300+ posts)
Joined: Jun 2005 Posts: 349 Likes: 2 | PS: I'm sure I'll be the biggest cynic of us all after a few of these "miracles" come and go 
Michael | 53 | SCC | Right Tonsil | Dx'd: 06-10-05 | STAGE IV, T3N2bM0 | 3 Nodes R Side | MRND & Tonsillectomy 06/29/05 Dr Fee/Stanford | 8 wks Rad/Chemo startd August 15th @ MSKCC, NY | Tx Ended: 09-27-05 | Cancer free at 16+ Yrs | After-Effects of Tx: Thyroid function is 0, ok salivary function, tinnitus, some scars, neck/face asymmetry, gastric reflux. 2017 dysphagia, L Carotid stent / 2019, R Carotid occluded not eligible for stent.2022 dental issues, possible ORN, memory/recall challenges.
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#39258 11-01-2005 04:40 PM | Joined: Nov 2002 Posts: 274 Platinum Member (200+ posts) | | Platinum Member (200+ posts)
Joined: Nov 2002 Posts: 274 | Good idea Mike. If no one else prolongs this thread, you can do it all by yourself! | | |
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