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c0ffee Offline OP
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Hello all,

My brother recently had a tongue lesion excised. The pathology report initially said "microinvasive" squamous cell carcinoma, with negative margins. When pressed what "microinvasive" meant, I was told 2mm of invasion. P16 testing was negative. Stage pT1NXMX.

A post-operative CT scan showed 2 "mildly enlarged" lymph nodes, which the surgeon felt were likely reactive.

Since the excision (4 months), my brother has been healing well, with no new sensitive areas.

The surgeon believes that the 2 nodes on CT are reactive. She feels that a PET-CT will likely result in an ambiguous answer (eg, reactive but cannot rule out metastasis), and thus force her to do a neck dissection, which she feels is not indicated.

I am driving myself and my brother crazy, trying to figure out what to do about those two nodes.

Does anyone have any personal experience, knowledge, or advice that can help me make this decision? What is the morbidity after a selective neck dissection (levels 1-4)?

Thank you
Tom


Tom

Brother of patient with posterior/lateral tongue SqCC:
Biopsy 4/2013 - High grade dysplasia
Excision 5/2013 - Microinvasive SqCC
Lymph node bx 11/2013 - Negative
pT1N0
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Better same safe than sorry. What was the differentiation of the tissue removed? If it was poor to moderately differentiated I would push for the dissection. Is he being seen at a cancer hospital? Take care


Cheryl : Irritation - 2004 BX: 6/2008 : Inflam. BX: 12/10, DX: 12/10 : SCC - LS tongue well dif. T2N1M0. 2/11 hemigloss + recon. : PND - 40 nodes - 39 clear. 3/11 - 5/11 IMRT 33 + cis x2, PEG 3/28/11 - 5/19/11 3 head, 2 chest scans - clear(fingers crossed) HPV-, No smoke, drink, or drugs, Vegan
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Why can't they do a FNA and see what that reveals? A simple needle stick and draw and a path report may solve this question.


David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
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c0ffee Offline OP
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I definitely agree - better safe than sorry. The only thing that gives me pause are the lingering effects from a selected neck dissection. I want to be aggressive, but not unreasonably so.

Has anyone had levels I-IV taken out? What are the issues after the healing is over?

As for the needle biopsy - I read that the FNA only samples 1mm of tissue, whereas the lymph node itself 10x bigger than that. Perhaps taking it out completely would be better.


Tom

Brother of patient with posterior/lateral tongue SqCC:
Biopsy 4/2013 - High grade dysplasia
Excision 5/2013 - Microinvasive SqCC
Lymph node bx 11/2013 - Negative
pT1N0
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I had all zones. I lost almost all mobility immediately after surgery, but with physio, got it all back. Started playing baseball the following spring. I still have some strength to get back, but that's coming with weight training.


Tina
Diag: Aug. 13/12
T3N0M0
50% + glossectomy and bilateral radical neck dissection, removal of nodes zones I - V
Surgery October 11/12
Chemo/rad on hold due to clear margins and nodes
Sept 21/13 clear CT with anomaly thought to be the artery, being watched closely.
Dec 16/13 - anomaly confirmed artery, all clear
nickname: "get 'r done"
Plans: kick cancer's butt
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"OCF Canuck"
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Yup! Ditto what she said... Hey Tina how was the scan?


Cheryl : Irritation - 2004 BX: 6/2008 : Inflam. BX: 12/10, DX: 12/10 : SCC - LS tongue well dif. T2N1M0. 2/11 hemigloss + recon. : PND - 40 nodes - 39 clear. 3/11 - 5/11 IMRT 33 + cis x2, PEG 3/28/11 - 5/19/11 3 head, 2 chest scans - clear(fingers crossed) HPV-, No smoke, drink, or drugs, Vegan
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Bah, still waiting on the results. Hopefully today or Monday.


Tina
Diag: Aug. 13/12
T3N0M0
50% + glossectomy and bilateral radical neck dissection, removal of nodes zones I - V
Surgery October 11/12
Chemo/rad on hold due to clear margins and nodes
Sept 21/13 clear CT with anomaly thought to be the artery, being watched closely.
Dec 16/13 - anomaly confirmed artery, all clear
nickname: "get 'r done"
Plans: kick cancer's butt
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FNAB are very accurate, just as good as a direct biopsy, and had had 7 or 8 myself, which were all on target. There are a number of types of neck dissections, and seven levels, I-VII, to the cervical neck, and depends on the location, type of cancer, which levels, and structures, are removed. Oral, tongue cancer usually involves level I first, oropharynx level II, so these are usually removed in the dissection up to IV or V, but there can be skip metastases or co-involvement with other levels. Every surgery has risks, and mine were positive so far, but all it takes is once to change all that, and our ENT's probably make it seem, sound easy, but it is a complicated surgery with all the vital structures affecting all aspects of life. I had three neck dissections, two were radical, all on the left side of the neck, going for my fourth.

Good luck.



10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs






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Paul is very fortunate to have gotten such good results with the fine needle biopsy. Ive seen many mixed review of this procedure. I seem to remember some members did not get conclusive results and still had to have a regular biopsy.

Best wishes!


Christine
SCC 6/15/07 L chk & by L molar both Stag I, age44
2x cispltn-35 IMRT end 9/27/07
-65 lbs in 2 mo, no caregvr
Clear PET 1/08
4/4/08 recur L chk Stag I
surg 4/16/08 clr marg
215 HBO dives
3/09 teeth out, trismus
7/2/09 recur, Stg IV
8/24/09 trach, ND, mandiblctmy
3wks medicly inducd coma
2 mo xtended hospital stay, ICU & burn unit
PICC line IV antibx 8 mo
10/4/10, 2/14/11 reconst surg
OC 3x in 3 years
very happy to be alive smile
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I had a FNAB and a core biopsy (core first). Both confirmed cancer in the node. The core biposy is taken im a similar manner to a FNAB but takes a larger piece of tissue to biopsy. Maybe push for a core biopsy. I would absolutely get a biopsy before a neck dissection.


Andrew
age 25

early 10/12 - enlarged lymph node area
01/13 SCC of L tonsil, L BOT, 2 L lymph nodes
stage IVa, T2N2bM0, HPV+

2/13 2 doses cisplatin big bag, 2 doses weekly cisplatin + 35x IMRT
4/13 TX finished
7/13 PET/CT - NED!
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