| Joined: May 2013 Posts: 63 "OCF Kiwi Down Under" Supporting Member (50+ posts) | OP "OCF Kiwi Down Under" Supporting Member (50+ posts) Joined: May 2013 Posts: 63 | Have any of you come across any relationship between a high ANA (antinuclear antibody) titre and SCC? Just asking as mine came back as 1:1280. It's a connective tissue marker but seems to also have a link to SCC?
2013 - 39yr old female, DX BOT SCC Stage IVA (T1N2bM0) HPV+ 28 May 13 - Pharangoscopy & tongue biopsy 29 May 13 - BOT Surgery & right ND (lvls 2-5) 31 May 13 - Hemorrhage, emergency trach, critical care BOT clr mgns, 9/67 nodes & extracapsular extension Finished 30 rads & chemo (cisplatin) stopped after 1 round due to hearing loss May 2015 - left supraclavicular swollen lymph node & area - CT planned 9 May
| | | | Joined: Jul 2012 Posts: 3,267 Likes: 4 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Jul 2012 Posts: 3,267 Likes: 4 | I never had it to my knowledge, and not too familiar with it, but It's used to test for autoimmune diseases. A healthy person can test positive, so It's not used for diagnosis, just rule out certain diseases, but then other specific tests can be done based on findings.
I heard of SCCA, Squamous Cell Carcinoma Antigen test being done to monitor for SCC recurrencent or persistent disease. but should not be solely relied on either.
My oncologist ordered a CEA test, carcineombryonic Anigen, for my next visit, maybe due to my anemia, and is mostlu used for other type of cancers especially colon, rectal, but also pancreas, breast, ovary, lung, but myndoctor mentioned before, she that she thought my CEA level would have gone down after surgery for my neck?
10/09 T1N2bM0 Tonsil 11/09 Taxo Cisp 5-FU, 6 Months Hosp 01/11 35 IMRT 70Gy 7 Wks 06/11 30 HBO 08/11 RND PNI 06/12 SND PNI LVI 08/12 RND Pec Flap IORT 12 Gy 10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux 10/13 SND 10/13 TBO/Angiograph 10/13 RND Carotid Remove IORT 10Gy PNI 12/13 25 Protons 50Gy 6 Wks Carbo 11/14 All Teeth Extract 30 HBO 03/15 Sequestromy Buccal Flap ORN 09/16 Mandibulectomy Fib Flap Sternotomy 04/17 Regraft hypergranulation Donor Site 06/17 Heart Attack Stent 02/19 Finally Cancer Free Took 10 yrs
| | | | Joined: Jul 2011 Posts: 945 "Above & Beyond" Member (500+ posts) | "Above & Beyond" Member (500+ posts) Joined: Jul 2011 Posts: 945 | I had the ANA titer as part of my RA diagnosis. I also had additional tests to rule out cancer. In my case, they were concerned that I might also have Lupus - but as Paul mentioned, the titer alone does not a diagnosis make. Maria
Last edited by Maria; 05-24-2013 04:37 PM.
| | | | Joined: Jul 2012 Posts: 3,267 Likes: 4 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Jul 2012 Posts: 3,267 Likes: 4 | A link by the ACS about tumor markers, and an explanation of each. No ANA on it. http://www.cancer.org/acs/groups/cid/documents/webcontent/003189-pdf.pdfAnother link for sreason for a CEA test in head and neck cancer, mostly used after suregry and or to monitor for a recurrence. http://www.ncbi.nlm.nih.gov/pubmed/1260711
10/09 T1N2bM0 Tonsil 11/09 Taxo Cisp 5-FU, 6 Months Hosp 01/11 35 IMRT 70Gy 7 Wks 06/11 30 HBO 08/11 RND PNI 06/12 SND PNI LVI 08/12 RND Pec Flap IORT 12 Gy 10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux 10/13 SND 10/13 TBO/Angiograph 10/13 RND Carotid Remove IORT 10Gy PNI 12/13 25 Protons 50Gy 6 Wks Carbo 11/14 All Teeth Extract 30 HBO 03/15 Sequestromy Buccal Flap ORN 09/16 Mandibulectomy Fib Flap Sternotomy 04/17 Regraft hypergranulation Donor Site 06/17 Heart Attack Stent 02/19 Finally Cancer Free Took 10 yrs
| | | | Joined: May 2013 Posts: 63 "OCF Kiwi Down Under" Supporting Member (50+ posts) | OP "OCF Kiwi Down Under" Supporting Member (50+ posts) Joined: May 2013 Posts: 63 | Yes I agree "the titre alone, does not a diagnosis make".. was just wondering. Thanks everyone. You're a wealth of collective knowledge. 
2013 - 39yr old female, DX BOT SCC Stage IVA (T1N2bM0) HPV+ 28 May 13 - Pharangoscopy & tongue biopsy 29 May 13 - BOT Surgery & right ND (lvls 2-5) 31 May 13 - Hemorrhage, emergency trach, critical care BOT clr mgns, 9/67 nodes & extracapsular extension Finished 30 rads & chemo (cisplatin) stopped after 1 round due to hearing loss May 2015 - left supraclavicular swollen lymph node & area - CT planned 9 May
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