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#11858 08-21-2007 04:15 PM
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Posts: 137
RileyMc Offline OP
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Help Cure Cancer!

http://folding.stanford.edu/

You can help by simply running a piece of software. Folding@Home is a distributed computing project -- people from through out the world download and run software to band together to make one of the largest supercomputers in the world. Every computer makes the project closer to our goals.

Folding@Home uses novel computational methods coupled to distributed computing, to simulate problems thousands to millions of times more challenging than previously achieved.

http://folding.stanford.edu/

WHAT HAVE WE DONE SO FAR AND WHERE ARE WE GOING?

Folding@Home has been a success. We have folded several small, fast folding proteins, with experimental validation of our method. We are now working to further develop our method, and to apply it to more complex and interesting proteins and protein folding and misfolding questions.

Since then, Folding@Home has studied more complex proteins, reporting on the folding of many proteins on the microsecond timescale, including BBA5, the villin headpiece, Trp Cage, among others.

More recently, we have been putting a great deal of effort into studying proteins relevant for diseases, such as Alzheimer's, Hunntington's, and Osteogenesis Imperfecta.

You can learn more about our results, on our Results Page and you can see specific , peer-reviewed scientific achievements on our Papers Page.

http://folding.stanford.edu/

Why not just use a supercomputer? Modern supercomputers are essentially clusters of hundreds of processors linked by fast networking. The speed of these processors is comparable to (and often slower than) those found in PCs! Thus, if an algorithm (like ours) does not need the fast networking, it will run just as fast on a supercluster as a supercomputer. However, our application needs not the hundreds of processors found in modern supercomputers, but hundreds of thousands of processors. Hence, the calculations performed on Folding@Home would not be possible by any other means! Moreover, even if we were given exclusive access to all of the supercomputers in the world, we would still have fewer cycles than we do with the Folding@Home cluster! This is possible since PC processors are now very fast and there are hundreds of millions of PCs sitting idle in the world.


It runs in the background, you can pause and stop it at any time if you are running something intense on your computer. But internet surfing, using word, or excel or similar generally leave room to spare for this work.
I encourage everyone to support this work.

I'm already running it so I hope it's real


dx 2/13/06. modified radical neck dissection 3/9/06 multiple biopsies of upper airway and direct laryngoscopy. 1 of 47 lymph nodes positive for metastatic undifferentiated carcinoma (lymphoepithelioma). Unknown primary. Finished radiation 5/24/06.
#11859 08-21-2007 04:17 PM
Joined: Jun 2007
Posts: 510
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Okay..I'll be the first...
What the hell are you talking about?


CG to 77 y/o hubby;SCC Alveolar Ridge; Wake Forest Baptist Hosp surgery: 07/19/07; bi mod radical resection/jaw replacement;
T2 N2-B M0 Stage IV-A
28 IMRT +
6 Paclitaxel/Carboplatin
Getting stronger every day!
#11860 08-21-2007 07:29 PM
Joined: Mar 2002
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Emmylou, as I understand it, you allow some organization to use the power of your personal computer to run computations. I am not comfortable downloading software that allows someone else to use my computer, but that's just me.

#11861 08-21-2007 11:14 PM
Joined: Nov 2006
Posts: 2,671
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I'm with you, Joanna - Seems like it is an educational institution, however could sensitive information from my computer become vulnerable in some way or more apt to attract a virus? This seems to appeal to one's altruistic nature, but I might feel better about it if OCF were to somehow receive a donation for each computer that "volunteers" to do this.


Anne-Marie
CG to son, Paul (age 33, non-smoker) SCC Stage 2, Surgery 9/21/06, 1/6 tongue Rt.side removed, +48 lymph nodes neck. IMRTx28 completed 12/19/06. CT scan 7/8/10 Cancer-free! ("spot" on lung from scar tissue related to Pneumonia.)



#11862 08-22-2007 03:07 AM
Joined: Aug 2006
Posts: 199
Me2 Offline
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I did a quick Google search and this seems to be a legitimate project out of Stanford - go to Google and enter "Folding@Home" into the seach bar.

Wikipedia has a nice explanation of the project http://en.wikipedia.org/wiki/Folding@home

Having said that, I, for one, am not willing to download this as I don't like to put anything on my computer that could compromise it in any way...


Ginny M. SCC of Left lateral tongue Dx 04/06,Surgery MDACC 05/11/06: Partial glossectomy with selective neck dissection. T1N0M0 - no radiation. Phase III clinical trial ("EPOC" trial)04/07 thru 04/08 because tests showed a 65% chance of recurrence. 10 Year Survivor!
#11863 08-22-2007 03:59 AM
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Posts: 41
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not for me either
as a now person,using that term very loose now,here i want to thank everyone here.
i want to get the story out about the dr mess ups and found a way yesterday to send a little to help ofc keep going.


paulie
#11864 08-22-2007 10:49 AM
Joined: May 2007
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This is very similar to the SETI@home and WorldCommunity Grid programs that I participate in. I would only imagine that they are using the same BIONIC software for this. BOINC is a program that lets you donate your idle computer time to science projects like SETI@home, Climateprediction.net, World Community Grid, and others.

In my experience with this type of software, there are no security problems as a direct result of using the software. If you computer is truly secure now you will be fine. They do disclose what type of information is collected about your computer configuration which is much better than what Micro$oft does.

I'll leave my computer security rant for another time.

Kevin


18 YEAR SURVIVOR
SCC Tongue (T3N0M0) diag 06/2006.
No evidence of disease 2010
Another PET 12-2014 pre-HBO, still N.E.D.


�Remember to look up at the stars and not down at your feet. It matters that you don't just give up.�
Stephen Hawking
#11865 08-22-2007 12:06 PM
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Posts: 666
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This is definigely real, and they are legitimate. The research is also suported by NIH or NSF I believe. It has been a while since i looked at their website.

It is basic research (infectious diseases and cancer)... do not expect a drug from this soon.

basically what it boils down to is this. They are running molecular dynamics programs to fond out how proteins fold/unfold and interact with each other. This is an extrmely complex problem. To give you an idea, if you run a 30ns (nanosecond!!) calculation on a cluster say (16-32 CPU) runing in parallel then this takes 2 weeks or longer. One way to overcome this is to use computers that are not doing anything.... like to one you use for typing and internet. It is an attractive idea to use resources that are avalable and presumably running and using energy anyway.

I am letting them use my home computer but not the laptop because that on is on/sleep/on/sleep all the time which is useless for them.

Markus


Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
#11866 08-22-2007 03:40 PM
Joined: Jun 2007
Posts: 510
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That's truly fascinating! Guess I'm a little behind in the technological field here in the backwoods of North Carolina...


CG to 77 y/o hubby;SCC Alveolar Ridge; Wake Forest Baptist Hosp surgery: 07/19/07; bi mod radical resection/jaw replacement;
T2 N2-B M0 Stage IV-A
28 IMRT +
6 Paclitaxel/Carboplatin
Getting stronger every day!
#11867 08-23-2007 01:42 AM
Joined: May 2007
Posts: 622
Likes: 1
"Above & Beyond" Member (500+ posts)
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Fascinating and cool technology, and you get a cool screen saver as well!

What a deal smile


18 YEAR SURVIVOR
SCC Tongue (T3N0M0) diag 06/2006.
No evidence of disease 2010
Another PET 12-2014 pre-HBO, still N.E.D.


�Remember to look up at the stars and not down at your feet. It matters that you don't just give up.�
Stephen Hawking
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