Amifostine has some significant side effects as in serious nausea. Even if you get past that, it only works in a small percent of the people that take it. However it does work in some people as a radio-protective agent for your salivary glands. I didn't get it, but were I to do this again, I would see if I could tolerate it and be one of the lucky ones that it worked on. 10 years out, the xerostomia is having serious consequences with my ability to fend off caries, perio disease and more. While I am on top of these things, it is a never ending battle each dental visit to deal with things that are going south. Saliva and the enzymes in it would be really nice to have some of. But remember that I went through radiation BEFORE IMRT, TOMO proton, or other more targeted and salivary gland sparing techniques... so my perspective, given the kinds and amount of radiation damage today being lesser, may be biased.

Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.