Geri

One thing I wish that I had done and did not with Erbitux was to get my biopsy tested for the K-ras gene mutation. Long story short: 65% have normal or "wild-type" K-ras gene but 35% have a mutation that keeps the EFGR response going despite Erbitux. The definite studies are in colon and lung cancer but even Big Pharm is advocating testing now. It is not a blood test but tests the DNA from a paraffin slide. Of course, ask your Doctor but I can't help but think that with the recurrence, maybe I had mutant K-ras as it does not affect the skin rash or side effects, just blocks the Erbitux from working. Or so I have read, please never rely upon me for medical advice but I am great on doctor questions.
Good luck


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13