I only have talked with about 10 patients who have had brachytherapy orally. I know about 10 more that had it in the southern regions for men's issues. I am certainly not an expert on implanted radioactive beads, but the whole reason for using them is that it limits the area of radiation, and the amount of collateral damage to other areas that those of us that had conventional radiation deal with, does not happen to seed patients. While again stating that my experience in this is limited since it is not the main mechanism of treatment for our kind of cancer, it seems unilkely tied to memory loss. Chemo brain, a well established issue and side effect is well known, and for most people transitory. And of course once you enter your 6th decade of lifem memory loss has been minimally happening for at least a decade already. (Obviously to different degrees in different people.... probably more in me.)