Just remember that the Tom's does not have any of the enzymes in it that Biotene has. These are naturally occurring in your saliva (which is now missing or diminished) and the main reason to use the Biotene product since they are part of your body's protection mechanism. Sometimes using a fluoride toothpaste or tray is important even if it is occasionally uncomfortable. When you start to develop decay issues, it is a never ending process of chasing it and expensive dentistry to correct things. None of the non prescription toothpastes have the level of fluoride that we need.