Getting the chemo weekly i.e. 7 times instead of 3 times a big dosage lowers the acute toxicity and should give more sustained level of drug. However, even so, I developed problems after just one cisplatin infusion (within 4 days)... My RO figured that was just in my head.... no kidding. In any event it got worse after the second infusion and we switched to carboplatin (higher dosage). I too was told that carboplatin is just as effective... which begs the obvious question.... why did we start with it. Cisplatin has been around a lot longer and MO's are more comfortable with it, plus it is also more active (hence the lower dosage compared to carboplatin).
Carboplatin does is lower your white blood count quite dramatically, cisplatin is also myelosuppressive but not as bad.

M