I have this problem (unrelated to H/N cancer) and when I fly I take 60 mg of Sudafed about 30 minutes before take-off and again 30 minutes before landing (if the flight lasts more than four hours). I also use Afrin nasal spray just before taking off and landing (the most difficult time), which is a big help.
There is also a product out there called "Earplanes" and if you Google that you'll get lots of info. I personally haven't tried them so can't speak to whether they work or not.
Since you have some pain pills, I'd go ahead and take them with you to use on your return trip if you find it was still too painful on your flight out.
Hope you have a GREAT trip!
-Tricia
BTW I think it is great you are getting away to a friend's wedding. I'm sure that will do your soul good and help with your overall health and healing to be at the wedding and wear that great dress!
