That is a sad list to read. I know two doctors whose specialty is genetics. When we talk, they have to water down their knowlege for me to even begin to wrap my mind around the whole thing. But in cancer, family clusters, and geographic clusters are a reality. Given your family's history, I would be diligent about the lifestyle things I could control, regular exams for those cancers that are avialable, and the exploration of any physical development that was out of the ordinary. This has to be balanced with a reasonable mental attitude towards things. It would be very easy to have something like this take a disproportionate slice out of the quality of your life, if it became an overly wieghted focus of your attention.