Valerie,
either the doctor is a perpetual optimist or a flat out liar. In my 5 years here I nave never heard of anyone's side effects peaking in the middle of treatment. Typically it is a few weeks POST Tx that the side effects peak. My experience with Cisplatin is that the side effects got progressively worse, to the point that they abandoned the 3rd treatment (it surely would have killed me).

About the insurance paying for nutrional supplements - they will ONLY if it is prescribed (Like Jevity). They will not pay for OTC stuff like Ensure, etc.

Like others have suggested here, slow, drip feeding, possibly at night might help. Hydration is a very big issue - 2-3 liters of water a day are required, especially since he is on Cisplatin. His kidneys can be permanently damaged by inadequate hydration and if he vomits he will have to start over abd replace the fluids lost. You should keep a log.

Compazine I used as a last resort, in suppository form, and it was marginally effective. Zofran works the best, but only 60% of the time. There are other anti-emetics as potent as Zonfran -grill your MO about it. Have a variety of anti-emetics to try. Zofran is only effective for 5 or so days at a time anyway.

If he needs hydration make an appointment with infusion have it done there - he will immediately begin to feel better (and it's a LOT faster and more comfortable than the ER). Most of us struggled with nausea. I puked so much I polished my teeth like glass from the stomach acid. It's tough to watch but to be expected. Cisplatin is some nasty sh*t.

Try this too, see if he can get his throat cleared BEFORE ingesting anything, especially in the morning. Suction machines, baking soda and salt (if he can tolerate the salt) rinses are other possibilities as well. Try a warm water rinse after a swish & spit of some "pink magic".

You just have to experiment and take it one day at a time. My days ranged from fair to horrific.

Watch for those constipation issues as well, they can also cause nausea when homeostatis is backed up.

Tomotherapy is nothing more than IMRT with adjustments made by CT scans (done adjunctively). So searching postings about IMRT should answer most of your questions about that.


Gary Allsebrook
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Dx 11/22/02, SCC, 6 x 3 cm Polypoid tumor, rt tonsil, Stage III/IVA, T3N0M0 G1/2
Tx 1/28/03 - 3/19/03, Cisplatin ct x2, IMRT, bilateral, with boost, x35(69.96Gy)
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"You are a mist that appears for a little while and then vanishes" (James 4:14 NIV)