My son also experienced he nausea symptoms earlier than what the doctor thought was the usual. He had to take two week long breaks towards the middle of Tx. He tried different nausea meds but it seems like the Zofran was the one that worked the best for him. I remember feeling so helpless and not knowing where to touch him or hold him because he was still so sore from the surgery. Smells also bothered him - he would lay on the couch with a quilt drawn up over his nose or wear one of those surgical masks. Later, when he lost his taste and the nausea wasn't as bad, smells became a good thing. He would smell everything because he said that with his taste gone, smelling something and breathing in deeply became a sort of "virtual taste". I also had to be careful to not even talk about food when he was feeling nauseous and wait until it had subsided to ask what I could get him to drink/eat. It does get better eventually. My son can now taste almost everything (except chocolate or anything sweet) and is eating and feeling so much better. Getting thru the TX "tunnel" can be really rough and the light at the end sometimes seems so far away, but we do get thru it and you can too. Keep checking in with the OCF site - I don't know what I would have done without it during some of the most difficult days.