A few years ago in Europe they did some clinical trials for re-irradiation of recurrent H&N cancer. The collateral damage was less than was anticipated as I remember.
There is one currently going on a UoW.
See http://www.mcw.edu/display/router.asp?docid=15349

Some of the following studies may already be completed, so the links are purely informational.

Hopkins had a phase three trial which is now closed but here is some info on it: http://www.radonc.jhmi.edu/html/trials/trial_R0421.html

Hopkins Results:

http://jco.ascopubs.org/cgi/content/full/24/17/2603?etoc

Fox Chase:

https://www.protonet.fccc.edu/cgi-bin/protocol/proto_summary.cgi?primary_site=Head+%26+Neck

I would explore EBT as well.

See: http://www.protons.com/proton-therapy/conditions-treated/head-and-neck.html


Hope this helps

Gary Allsebrook
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Dx 11/22/02, SCC, 6 x 3 cm Polypoid tumor, rt tonsil, Stage III/IVA, T3N0M0 G1/2
Tx 1/28/03 - 3/19/03, Cisplatin ct x2, IMRT, bilateral, with boost, x35(69.96Gy)
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"You are a mist that appears for a little while and then vanishes" (James 4:14 NIV)