Hi Micheal, Jack was able to successfully complete the entire course of amifostine. He thinks it helped with the saliva and preventing fibrosis. If you'e going to do it make sure you follow the recommended protocols for drinking 2-3 quarts of water, and using heavy duty anti-nausea drugs (Jack used zofran twice a day every day as a precaution, and compazine for breakthru nausea).

I can't stress the need for hydration strongly enough. It helps with all the side effects. He had to drink 16-24 oz of water 90 minutes before the shot. Jack thought getting the shot itself was painful but he'd also do it again. Everyone's experience is different and you're the only one that can decide whether the potential benefit is worth the potential side effects. This is only 1 of many times you'll be faced with that. As Brian points out you can always stop the treatment if you're having any issues with it.

Regards JoAnne