Insomnia is common and I still have it 4+ years later!

Zofran is the anti-emetic of choice but it has some limitations. First it is mainly effective for 3-5 days at a time (according to the manufacturer), then you must switch to something else for a while, secondly it is effective in about 60% of patients. There are other equally effective anti-emetics on the market now.

My 2nd Cisplatin Tx reaction was so severe that they decided not to give me a third.

Fortunately I didn't have any hearing problems and they are rather rare as I understand. As Steve suggested, do pay close attention to any changes and discuss it with your MO immediately. You should have had a baseline hearing test prior to starting treatment and one during treatment and one after.

I will emphasize again what others have said that hydration is not only key to protecting your other organs from permananet damage but also for the drug to work properly.