Here are the manufacurer's instructions:

"The patch should be applied to a clean, dry area on the upper arm or back. If necessary, clip hair from the site prior to applying the patch. Remove the the patch from the package, peel off the protective strip and immediately apply to the skin. Press firmly for 10-20 seconds to make sure that the patch stays in place. Be sure that the edges are held firmly to the skin. Wash your hands after applying the patch. Each patch may be worn for 72 hours even while showeting or bathing. Remove the patch carefully and immediately flush down the toilet. Apply each new patch to a different area to prevent skin irritation. Use this medication exactly as prescribed by your doctor. Do not increase your dose, use it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Also, if used for an extended period of time, do not suddenly stop using this drug without your doctors approval. Over time, this drug may not work as well. Consult your doctor if this medication is not relieving the pain sufficiently."