About the important hydration with Amifostine: my husband was hydrated every day, prior to the Ethyol being administered, via his IV port. This was a very easy way to get the hydration. He always felt alot better after the hydration. When he wasn't in for treatments over the weekend, I'd continue the hydration through the port. The difference it made in how he felt was remarkable. The radiation nurses would load us up on Fridays with all the needed supplies.

He had radiation for 37 days and Ethyol for every day but the last day . At almost 3 years out, the doctors seem pretty pleased with his mouth moisture level, even though he thinks it is very poor.

As Gail mentioned, the right mix of anti-nausea meds and the right timing is also very important. Pester the doctors about it until they find the right combo.

Best to you and your family,
Anita