You mean Amofostine? I don't recall anyone here yet being able to tolerate the whole treatment. It can cause extreme nausea as well.

I too had extreme nausea issues with Cisplatin. Usually within the first week after the infusion. I ended up having to use compazine suppositories because I couldn't keep anything down. The nausea got worse with each treatment. You just have to ride it out. I know it's very hard to watch a loved one go through this. Keep after the docs for nausea control - there are other things to try.

He MUST stay hydrated! Cisplatin is very hard on the kidneys and must be flushed out. If it is allowed to concentrate it can cause permanent kidney and possible liver damage. He will feel much better after hydration. If he can't swallow or keep anything down then make an appointment in infusion for rehydration. He should be taking in 2-3 liters of water daily.