larryb, statistically, one of the risk factors for esophageal cancer is being a head and neck cancer patient/survivor. A couple of others, which we have heard before, are smoking and alcohol consumption. Untreated GERD can damage cells in the esophagus, leading to a condition known as Barrett's Esophagus, in which cells are classified as pre-cancerous. Some damage can be healed by the ingestion of proton pump inhibitors (Prilosec is one). The generic Zantac you are taking will definitely relieve symptoms, but is a step down from the PPIs in treatment terms. This is a highly simplified overview. For more specific and detailed information do a search on http://www.medlineplus.gov

Just one more thing to keep on top of.