Leukoplakia develops into cancer around 1 in 20 times according to research, but it can take many, many years before anything develops. And like Brian typed, have it examined often, early diagnosis means less complications. I know it's hard to do but don't worry. According to my dentist I have leukoplakia also. I just figure that I will have it looked at often by a Maxiofacial Surgeon whom only charges about $40.00 per examination. A small price to pay for a piece of mind. If something develops and it is the big C then I'll worry.