Hi, Linda, in our experience, the chemo was pretty much a non-issue [John did lose his hair, and got tired,] but never had nausea. But to quote others here "the radiation kicked his butt". So expect that after the first couple of rad txs., he could start to feel lousy. If you work, you may need to take some time off, or rearrange your schedule to be available to him. Is he going to have a peg tube? If not, you need to have a good blender or food processor handy, and start stocking up on soups, shake recipes, etc. And do a search here of recipes that are high calorie and easy to swallow. I think it's better to take this treatment one phase at a time and learn [ask questions] at the beginning of that phase what issues you may need to deal with. As a caregiver, I would encourage you to get as organized as you can. Odds are, you will inherit his share of "household chores and responsibilities" for a period of time, plus it may well become your responsibility to keep up with meds,appointments, Ins. claims,etc. I've had trouble finding enough hours in the day many times. And Last, but not least, it's pretty necessary for you to stay healthy during his treatment, so sleep and "down time" is going to be important for you. You can get lots of support here- so hang in. Amy in the Ozarks