Hello,

I was diagnosed with PVL 8 years ago. I underwent yearly laser ablations and scalpel excisions of the affected sites. I never had any dysplasia from the mulifocal yearly biopsies. Everything seemed to be under control...But, I developed a periodontal infection near a tooth where the Leukoplakia was present. The tooth was pulled, but the infection never healed and I was eventually diagnosed with SCC.

PVL is an insidious disease that nearly always transforms into cancer. My advice is to be aggressive early on and remove the Leukoplakia lesions on some timeline - mine was annual.

There are several publications that I have seen online that focus on PVL, but you are mostly confined to the seeing only the abstract unless you pay for the paper.

Unfortunately, because it is so rare, there hasn't been much research into it.


I wish you the best.


Last edited by MST; 01-09-2020 01:35 PM.