I'm Suzi, age 57 in Houston with a 2 year history of mouth sores. I assumed it was due to taking methotrexate for my Rheumatoid Arthritis, since I've been on and off that for roughly 20 years. I seemed to get more sores after each dental visit (complete upper and lower dentures in 2017) despite taking foluc acid with my mtx every week. I also contracted both herpes and HPV back in my teens when I wasn't quite so careful. My rheumatologist took me off the methotrexate back in June due to a pretty extreme number of sores in my mouth and GP put me on Valtrex, a dental paste and troches to dissolve orally 5 times a day.
At that time she noticed a lesson under my tongue, which I chalked up to being just another sore even though she told me to get it checked by an ENT and warned me it probably needed to be biopsied. Did I listen? Nope. Now I've found 2 more raised areas in my mouth and another whitish-patch which I wouldn't really call a sore. Went back on the Valtrex a week ago and no change. I'm back on the methotrexate, have added leucovorin. So, guess I'll be finding an ENT this week to find out if something is actually growing in there. And yes, I've been smoking for 40 years so I'm not very hopeful. Would be my luck I spend 20k on new teeth and end up with cancer. So glad I found this group and keeping my fingers crossed. That's my introduction!