They say it takes 50Gy and above to kill SCC, but your right, higher is really needed, and went on to get more opinions when two centers only offered 50Gy for my recuurence, which is often the case, 50Gy, 25 sessions, but I had boost doses of IORT too at another CCC, which RO said 50Gy wouldn't work, so my total dosage was way beyond that. Certain primary areas need more like 66-70Gy, and other specific areas usually less, depending on many factors, including toxicity level limits. It's also more the mandible, than the Maxilla at risk for ORN, 60/30, those that had brachytherapy, used biphosantates, besides having had extractions, and depending on radiation dosages, areas. We probably see more ORN in oral vs oropharyngeal radiated cancers. This is just a discussion, nothing in front of me with stats, but my recollection. I posted a while back an article on ORN.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs