The Dr referenced above uses Pentoxyphyline, alpha Tocopherol and clodronate. The first two help blood flow better and the clodronate reduces blood calcium. It is a bisphosphonate which is a class of drugs used to treat osteoporosis. Even in trials up to 24 months as soon as the Pentoxyphyline/alpha Tocopherol was stopped, the fibrosis and associated problems returned. I saw radical results from a combination of the first two within days that only got better almost daily for 2 months. Within a week of stopping a fibrotic mass appeared around my stomach area.

It is strange that the actual mechanisms used by Pentoxyphyline to improve blood viscosity and the calcium improvements seen with clodronate are not fully understood. I stopped the protocol when it appeared I developed a bone marrow issue with all blood counts reducing. The worrisome part was the reduction in reticulolytes, the immature red blood cells produced by the marrow and released into the blood to become grown up red blood cells. Aplastic anemia has been one side effect of concern noted in the Pentoxyphyline/alpha Tocopherol studies back to the early 90's. However, aplastic anemia as well as MDS is also a known late effect complication of radiation treatment. Larry Hagman and Robin Roberts of Good Morning America both developed MDS post treatment. Larry Hagman's rapidly progressed to leukemia and took his life quickly. Robin received a full bone marrow transplant and recovered over many months.

The protocol developed by the above referenced doctor has also shown promise in treating osteoradionecrosis according to some of the papers.

Great find and an important piece in reducing calcium buildup that causes muscle binding, nerve entrapment pain and eventual fibrosis.