Most HPV-16 occurr in the oropharynx, not the oral mouth, tongue, not saying it can't happen, but even guidelines don't suggest HPV testing in these areas, but there are lots of unexplained cancer in the mouth in those with no history of drinking, smoking, and not HPV16 related. Like head and neck cancer, anything unusual that lasts more than 2-3 weeks, should be checked by your doctor, and glad you are doing that. I don't think being HPV16 positive in the head and neck protects you from another HPV16 related cancer in the anogenital area, although I heard you can't be infected twice with the same HPV, it would be rare, but it could be a different HPV strain or a simutaneous infection at the same time, which sounds rare also. They haven't proven a link with anogenital HPV cancer to Head and Nevk, but read women who have anogenital HPV are at higher risk for head and neck cancet, although there are over 150 strains, and only 15 are high risk for cancer, so I don't know what that means, maybe just effecting the immune system.

We had a lengthy discussion about this under HPV, one which I may have posted under "HPV Related Questions" in the after treatment section.

Hopefully it is nothing major, and again, it's not cancer until proven by biopsy, but feel your concern. Good luck.