I had radiation three times, going for my fourth tomorrow with intraoperative radiation also, which I had last year. Yes, you can have more radiation with the flap, and is like having new unradiated tissue, plus other dose painting techniques with IMRT. Also IORT is very specific with protecting vital areas with lead shied, being moved out of the radiated field. I can't guarantee anything, and maybe discuss further with your doctor. Good luck.