I heard many people with this complaint, and no clear answer what is the cause, and I have no definite answer either, and believe most likely It is from canker sores, fever blisters, water blister, caused by the the herpes simplex virus, HSV-1, which can be reactivated by illness, poor nutrition, radiation, chemo, etc. Another I heard was from acidic foods, so staying away from them may help, and then heard the usual, it's part of the healing process, but I want to know why.
This is going to bother me until I find out lol. My RO visit is not until August